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  1. 1:大学
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Changes in Acute-Phase Proteins and Cytokines in Serum and Milk Whey from Dairy Cows with Naturally Occurring Peracute Mastitis Caused by Klebsiella pneumoniae and the Relationship to Clinical Outcome

http://hdl.handle.net/10659/3249
http://hdl.handle.net/10659/3249
773477de-6780-456f-9886-43be6616fc11
Item type 学術雑誌論文 / Journal Article(1)
公開日 2013-06-04
タイトル
タイトル Changes in Acute-Phase Proteins and Cytokines in Serum and Milk Whey from Dairy Cows with Naturally Occurring Peracute Mastitis Caused by Klebsiella pneumoniae and the Relationship to Clinical Outcome
言語
言語 eng
キーワード
主題Scheme Other
主題 acute-phase protein
キーワード
主題Scheme Other
主題 cytokine
キーワード
主題Scheme Other
主題 dairy cow
キーワード
主題Scheme Other
主題 Klebsiella pneumoniae
キーワード
主題Scheme Other
主題 peracute mastitis
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 HISAEDA, Keiichi

× HISAEDA, Keiichi

WEKO 4919

HISAEDA, Keiichi

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ARIMA, Haruki

× ARIMA, Haruki

WEKO 4920

ARIMA, Haruki

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SONOBE, Takahisa

× SONOBE, Takahisa

WEKO 4921

SONOBE, Takahisa

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NASU, Masanobu

× NASU, Masanobu

WEKO 4922

NASU, Masanobu

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OGIWARA, Katsuro

× OGIWARA, Katsuro

WEKO 4923

OGIWARA, Katsuro

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KIRISAWA, Rikio

× KIRISAWA, Rikio

WEKO 4924
教員総覧 cb22d3fb8f00ce52677a9a637214e82c

KIRISAWA, Rikio

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TAKAHASHI, Tatsufumi

× TAKAHASHI, Tatsufumi

WEKO 4925

TAKAHASHI, Tatsufumi

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KIKUCHI, Naoya

× KIKUCHI, Naoya

WEKO 4926

KIKUCHI, Naoya

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NAGAHATA, Hajime

× NAGAHATA, Hajime

WEKO 4528
教員総覧 cb22d3fb8f00ce528832880dc22347c6

NAGAHATA, Hajime

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抄録
内容記述タイプ Abstract
内容記述 This study was conducted to evaluate the changes in acute-phase proteins and cytokine concentrations in dairy cows with naturally occurring peracute Klebsiella pneumoniae (K. pneumoniae) mastitis and their association with the outcome of the disease. Seventeen Holstein cows with K. pneumoniae mastitis from 8 dairy farms were divided on the basis of outcome after local and systemic therapy into 2 groups comprising 8 euthanized cows and 9 that recovered. Changes in acute-phase proteins and cytokine concentrations in cows with K. pneumoniae mastitis were evaluated at the onset of the disease (day 0) and at days 3, 7 and 14 after therapy and compared with those of 13 healthy dairy cows. The concentrations of haptoglobin (Hp) and interleukin (IL)-6 in serum and α1-acid glycoprotein and IL-1β in serum and whey on day 0 were significantly (P<0.05) higher in the euthanized cows than in those that recovered and the healthy cows. A correlation (r=0.90, P<0.01, n=17) was found between IL-6 and Hp concentrations in sera from recovered and euthanized cows at day 0. This indicated that serum concentrations of Hp and IL-6 at the initial examination were prognostic factors for survival, and the cutoff values were 2,020 μg/ml and 32 ng/ml, respectively. These results suggest that IL-6 and Hp concentrations are involved in the manifestation of K. pneumoniae mastitis and may be possible indicators of the prognosis of peracute K. pneumoniae mastitis.
書誌情報 The journal of veterinary medical science

巻 73, 号 11, p. 1399-1404, 発行日 2011-11
DOI
識別子タイプ DOI
関連識別子 10.1292/jvms.10-0403
出版者
出版者 日本獣医学会
資源タイプ
内容記述タイプ Other
内容記述 Article
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