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Effects of Collagen-Derived Oligopeptide Prolylhydroxyproline on Differentiation of Mouse 3T3-L1 Preadipocytes
http://hdl.handle.net/10659/3458
http://hdl.handle.net/10659/3458f359bdbc-a5f7-4a32-a570-320408c07c5b
名前 / ファイル | ライセンス | アクション |
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S-2013-98_minaguchi.pdf (2.5 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-06-16 | |||||
タイトル | ||||||
タイトル | Effects of Collagen-Derived Oligopeptide Prolylhydroxyproline on Differentiation of Mouse 3T3-L1 Preadipocytes | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | collagen peptide | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | prolylhydroxyproline | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | adipocyte | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 3T3-L1 cell | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | proton-coupled oligopeptide transporter | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
MINAGUCHI, Jun
× MINAGUCHI, Jun× TOMETSUKA, Chisa× KOYAMA, Yoh-ichi× KUSUBATA, Masashi× NAGAYASU, Aya× SAWAYA, Satoe× SHIGA, Tetsuko× SHIMA, Hanae× HARA, Takahiro× TAKEHANA, Kazushige |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Beneficial effects of collagen peptide ingestion to reduce serum triacylglycerides have been reported, suggesting that the physiological conditions of adipocytes are modulated following collagen peptide ingestion. In this study, the effects of prolylhydroxyproline, a major digestive product of ingested collagen peptide in the blood, on the differentiation of mouse 3T3-L1 preadipocytes in vitro were investigated. 3T3-L1 preadipocytes were induced to differentiate to adipocytes and treated with prolylhydroxyproline, or with an amino acid mixture of proline and hydroxyproline as a control. The amount of lipid was not affected by these treatments. However, the size of the lipid droplet was significantly smaller when treated with prolylhydroxyproline compared to the amino acid mixture or the non-treated control. Proton-coupled oligopeptide transporters were expressed in non-differentiated and/or differentiated 3T3-L1 cells. These results suggest that prolylhydroxyproline might modulate the morphology of lipid droplets by incorporation into adipocytes through the transporters. | |||||
書誌情報 |
Food Science and Technology Research 巻 18, 号 4, p. 593-599, 発行日 2012 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1344-6606 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3136/fstr.18.593 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 社団法人日本食品科学工学会 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |