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Morphological and Biochemical Analysis of Intact and Opaque Cornea in Dogs

http://hdl.handle.net/10659/2847
http://hdl.handle.net/10659/2847
6f9a808a-7ddb-4a8b-b64f-b54cb7adabc7
名前 / ファイル ライセンス アクション
S-2011-154_Minaguchi.pdf S-2011-154_Minaguchi.pdf (2.9 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2012-10-01
タイトル
タイトル Morphological and Biochemical Analysis of Intact and Opaque Cornea in Dogs
言語
言語 eng
キーワード
主題Scheme Other
主題 Collagen fibril
キーワード
主題Scheme Other
主題 Glycosaminoglycan
キーワード
主題Scheme Other
主題 Opaque cornea
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 HIROOKA, Masamitsu

× HIROOKA, Masamitsu

WEKO 6489

HIROOKA, Masamitsu

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IGARASHI, Osamu

× IGARASHI, Osamu

WEKO 6490

IGARASHI, Osamu

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NAGAYASU, Aya

× NAGAYASU, Aya

WEKO 6491

NAGAYASU, Aya

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MINAGUCHI, Jyun

× MINAGUCHI, Jyun

WEKO 5069
教員総覧 b3feebe96363a5f7b7ccf1252aa990bd

MINAGUCHI, Jyun

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HOSAKA, Yoshinao Z.

× HOSAKA, Yoshinao Z.

WEKO 6492

HOSAKA, Yoshinao Z.

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植田, 弘美

× 植田, 弘美

WEKO 4637
教員総覧 9436

en UEDA, Hiromi

ja 植田, 弘美


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TANGKAWATTANA, Prasarn

× TANGKAWATTANA, Prasarn

WEKO 6493

TANGKAWATTANA, Prasarn

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TAKEHANA, Kazushige

× TAKEHANA, Kazushige

WEKO 4638
教員総覧 da802e47c9b2cc7eaaf5c69bf1b24b91

TAKEHANA, Kazushige

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抄録
内容記述タイプ Abstract
内容記述 The arrangement of collagen fibrils and glycosaminoglycans (GAGs) in substantia propria are important for maintaining transparency of the cornea. Interferences in collagen fibrils and GAG production could be adversative to corneal integrity. In this study, six dogs consisting of four Beagles with normal cornea (normal), one Beagles with opaque cornea (sample No.1) and one Shih Tzu with neovascularization opaque cornea (sample No.2) were used. All samples were observed morphologically by light and electron microscopes to obtain diameter and distribution of collagen fibrils in substantia propria and were performed biochemically to investigate into GAGs and collagen types. The average diameter of collagen fibrils in the intact cornea of normal, sample No.1 and No.2 was 33.2, 35.0 and 25.0 nm, respectively. The percentage of matrix per unit area was 67% in normal, 87% in sample No.1 and 28.3% in sample No.2. The type III collagen ratio was 25.3% in normal, 21.3% in sample No.1 and 35.8% in sample No.2. The relative amount of heparan sulfate, chondroitin sulfate, dermatan sulfate and keratin sulfate was 1.5, 9.7, 51.1 and 37.7% in normal, 3.3, 26.0, 45.7 and 23.7% in sample No.1 and 1.2, 18.0, 16.6 and 54.1% in sample No.2. Hyaluronic acid was found only in sample No.1 with a relative amount of 1.3%. Since there was some relationship between collagen formation and GAGs composition, it might be speculated that disturbance in arrangement of collagen fibrils and GAG metabolism especially in substantia propria would bring up opacity of the cornea.
書誌情報 Okajimas Folia Anatomica Japonica

巻 87, 号 2, p. 59-64, 発行日 2010-08
ISSN
収録物識別子タイプ ISSN
収録物識別子 0030-154X
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.2535/ofaj.87.59
権利(URI)
権利情報 https://www.jstage.jst.go.jp/article/ofaj/87/2/87_2_59/_article | https://www.jstage.jst.go.jp/article/ofaj/87/2/87_2_59/_article
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
出版者
出版者 オカジマ・フォリア アナトミカ・ヤポニカ編集部
資源タイプ
内容記述タイプ Other
内容記述 Article
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