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Peripheral Lymphocyte Subsets as a Prognostic Indicator of Mortality and Morbidity in Healthy Dogs
http://hdl.handle.net/10659/3477
http://hdl.handle.net/10659/347788d4b7a0-7690-4d07-9475-bf7aae3a4353
名前 / ファイル | ライセンス | アクション |
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S-2013-122_endo.pdf (1.3 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-06-16 | |||||
タイトル | ||||||
タイトル | Peripheral Lymphocyte Subsets as a Prognostic Indicator of Mortality and Morbidity in Healthy Dogs | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | aging | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | canine | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | lymphocyte subset | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | morbidity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mortality | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
WATABE, Ai
× WATABE, Ai× HANAZONO, Kiwamu× KOMATSU, Takahiro× FU, Dah-Renn× ENDO, Yoshifumi× KADOSAWA, Tsuyoshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | To evaluate the relationship among immune status and increased morbidity and mortality, peripheral blood lymphocytes (CD3+, CD4+, CD8+ and CD21+ cells) from 32 healthy dogs over 8 years of age were analyzed. Twenty-five of the 32 dogs were followed-up for 3 years after the analysis; and 14 dogs were found to be diseased, and nine dogs died. There was no notable difference between the ages of the dogs that died compared with the ones that survived. The relative percentage of CD4+ and the CD4+:CD8+ ratio decreased notably in dogs falling ill compared with healthy dogs. The relative percentage of CD3+ lymphocytes showed a notable decrease in dogs that died within 3 years in comparison with dogs that survived. In a discriminant analysis of morbidity and mortality, most patients were correctly classified as diseased or not and surviving or dead, respectively. These results indicate that the immunophenotypes of peripheral blood lymphocytes in older dogs offer promise as parameters for evaluating mortality and morbidity. | |||||
書誌情報 |
Journal of Veterinary Medical Science 巻 74, 号 7, p. 937-943, 発行日 2012-07 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0916-7250 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1292/jvms.11-0554 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 日本獣医学会 | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |