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Sequence Variation in Hepatitis E Virus Genotypes 3 and 4 from Swine Fecal Samples in Japan
http://hdl.handle.net/10659/1823
http://hdl.handle.net/10659/18232b3cbd86-977f-4521-81b9-86de256fadfc
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
S-807_Hagiwara.pdf (642.1 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2011-03-31 | |||||
| タイトル | ||||||
| タイトル | Sequence Variation in Hepatitis E Virus Genotypes 3 and 4 from Swine Fecal Samples in Japan | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Sapsutthipas, Sompong
× Sapsutthipas, Sompong× Urayama, Takeru× Yamate, Masanobu× Tsujikawa, Muneo× Nishigaki, Hiromi× OGIWARA, Katsuro× Yunoki, Mikihiro× Yasue, Hiroshi× Sato, Kunio× Ikuta, Kazuyoshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Hepatitis E virus (HEV) is a causative agent for hepatitis. HEV is transmitted via the fecal-oral route through contaminated drinking water and induces zoonotic infections through eating uncooked and undercooked meat of deer, wild boar, and swine. In Japan, genotypes 3 (G3) and 4 (G4) are prevalent in domestic swine. Here, we examined the genetic variation among HEVs derived from swine fecal samples in Japan. A total of 320 samples were collected at 32 commercial farm facilities (1 fecal sample from each of 10 pig houses in individual farms). Viral RNA amplification at open reading frame (ORF) 3 was possible in 159 (49.7%) of the fecal samples. For genotyping, the same samples were subjected to amplification at ORF2 and the resulting amplicons were sequenced. The results revealed that all the HEVs in each farm belonged to the same cluster of G3 and G4: G3JP in 8 farms, G3SP in 4 farms, G3US in 6 farms, and G4JP in 2 farms, unclassified G3 in 2 farms, unable to decide due to a low rate of amplification in 5 farms, and no detection in 5 farms. Interestingly, the HEVs from one farm were more homogeneous than those of the same cluster that was derived from other farms. Thus, the efficiency of farm-to-farm transmission of HEVs is likely to be low and HEV seems to have evolved independently at each farm in Japan. | |||||
| 書誌情報 |
The Open Veterinary Science Journal 巻 3, p. 68-75, 発行日 2009-11 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1874-3188 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.2174/1874318800903010068 | |||||
| 権利（URI） | ||||||
| 権利情報 | http://creativecommons.org/licenses/by/2.0/ | http://creativecommons.org/licenses/by/2.0/ | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | Bentham Open | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
