ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

  1. 1:大学
  2. 2.獣医学群
  3. 1.獣医学類
  4. 学術論文(雑誌)

Evaluation of a combination of alfaxalone with medetomidine and butorphanol for inducing surgical anesthesia in laboratory mice

http://hdl.handle.net/10659/00005422
http://hdl.handle.net/10659/00005422
dcdd0cd0-53b0-4fad-8509-f23900accb40
名前 / ファイル ライセンス アクション
R-2017-161_Yamashita.pdf R-2017-161_Yamashita.pdf (1.9 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2018-04-12
タイトル
タイトル Evaluation of a combination of alfaxalone with medetomidine and butorphanol for inducing surgical anesthesia in laboratory mice
言語
言語 eng
キーワード
主題Scheme Other
主題 alfaxalone
キーワード
主題Scheme Other
主題 anesthesia
キーワード
主題Scheme Other
主題 butorphanol
キーワード
主題Scheme Other
主題 medetomidine
キーワード
主題Scheme Other
主題 mice
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Higuchi, Shota

× Higuchi, Shota

WEKO 16159

Higuchi, Shota

Search repository
Yamada, Riku

× Yamada, Riku

WEKO 16160

Yamada, Riku

Search repository
Hashimoto, Asami

× Hashimoto, Asami

WEKO 16161

Hashimoto, Asami

Search repository
三好, 健二郎

× 三好, 健二郎

WEKO 4519
教員総覧 9455



Search repository
山下, 和人

× 山下, 和人

WEKO 4715
教員総覧 9433

en YAMASHITA, Kazuto

ja 山下, 和人


Search repository
Ohsugi, Takeo

× Ohsugi, Takeo

WEKO 16162
教員総覧 1f8c57c46035d927b5fed8fef38c7885

Ohsugi, Takeo

Search repository
抄録
内容記述タイプ Abstract
内容記述 The anesthetic effects of alfaxalone were investigated in mice. Mice were administered alfaxalone (100 mg/kg) alone or the combinations of 0.3 mg/kg of medetomidine and 5 mg/kg of butorphanol with alfaxalone at doses of 20 mg/kg (M/B/A20), 40 mg/kg (M/B/A40), 60 mg/kg (M/B/A60), or 80 mg/kg (M/B/A80). Control mice received 0.3 mg/kg of medetomidine, 4 mg/kg of midazolam, and 5 mg/kg of butorphanol (M/M/B). Each drug was administrated by intraperitoneal (IP) or subcutaneous (SC) routes. M/M/B IP did not achieve surgical anesthesia but M/M/B SC achieved surgical anesthesia within 10 min after administration and maintained anesthesia for 45 min. The anesthetic scores were very low after IP or SC administration of alfaxalone alone. M/B/A20 IP and SC did not achieve surgical anesthesia. M/B/A40 IP did not achieve surgical anesthesia but M/B/A40 SC achieved surgical anesthesia within 10 min after administration and maintained anesthesia for 35 min. M/B/A60 SC achieved surgical anesthesia within 5 min after administration and maintained anesthesia for 75 min. By contrast, M/B/A60 IP did not achieve surgical anesthesia. M/B/A80 SC achieved surgical anesthesia within 5 min after administration and maintained anesthesia for 85 min. By contrast, M/B/A80 IP did not achieve surgical anesthesia and one mouse died about 10 min after drug administration. Administration of atipamezole rapidly reversed anesthesia induced by M/B/A60 in mice. These results suggest that M/B/A60 SC, an alfaxalone-based combination, is suitable for inducing surgical anesthesia in laboratory mice.
書誌情報 Japanese Journal of Veterinary Research

巻 64, 号 2, p. 131-139, 発行日 2016-05
ISBN
識別子タイプ ISBN
関連識別子 0047-1917
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 http://dx.doi.org/10.14943/jjvr.64.2.131
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
出版者
出版者 Graduate School of Veterinary Medicine, Hokkaido University
資源タイプ
内容記述タイプ Other
内容記述 Article
戻る
0
views
See details
Views

Versions

Ver.1 2023-06-19 08:06:20.000392
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR 2.0
  • OAI-PMH JPCOAR 1.0
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3