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Anesthetic and Cardiorespiratory Effects of Propofol, Medetomidine, Lidocaine and Butorphanol Total Intravenous Anesthesia in Horses
http://hdl.handle.net/10659/3845
http://hdl.handle.net/10659/3845c19340d3-94d1-4a88-91a9-caae49468d2a
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2015-05-12 | |||||
タイトル | ||||||
タイトル | Anesthetic and Cardiorespiratory Effects of Propofol, Medetomidine, Lidocaine and Butorphanol Total Intravenous Anesthesia in Horses | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | butorphanol | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | horse | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | lidocaine | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | medetomidine | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | propofol | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
ISHIZUKA, Tomohito
× ISHIZUKA, Tomohito× ITAMI, Takaharu× TAMURA, Jun× SAITOH, Yasuo× SAITOH, Motoaki× UMAR, Mohammed A.× 三好, 健二郎× 山下, 和人× MUIR, William W. |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Anesthetic and cardiorespiratory effects of medetomidine, lidocaine, butorphanol and propofol total intravenous anesthesia (MLBP-TIVA) were evaluated in horses undergoing an experimental surgery. Ten horses were premedicated with an intravenous injection (IV) of medetomidine (5μg/kg) and butorphanol (20μg/kg). Anesthesia was induced by administration of 1% propofol (3mg/kg, IV) at a rate of 1 mg/kg/min (n=5, group-1) or 2% propofol administered at a rate of 6 mg/kg/min (n=5, group-2) following administration of lidocaine (1 mg/kg, IV) and then maintained by infusions of propofol, medetomidine (3.5μg/kg/hr), lidocaine (3mg/kg/hr) and butorphanol (24μg/kg/hr). The mean durations of anesthesia and propofol infusion rate required for maintaining surgical anesthesia were 130±17 min and 0.10±0.01mg/kg/min in group 1 and 129±14 min and 0.10±0.02 mg/kg/min in group 2. Four horses in group 1 and 2 horses in group 2 paddled following recumbency during induction of anesthesia. The median quality scores for induction (0-4: poor-excellent) and recovery (0-5: unable to stand-excellent) were 3 and 4 for both groups, respectively. Transition to anesthesia (the first 20-min period after induction) was uneventful in group 2, while all horses showed a light plane of anesthesia in group 1. The quality score (0-3: poor-excellent) for the transition to anesthesia in group 2 was significantly higher than in group 1 (median 3 versus 1, P=0.009). Heart rate and arterial blood pressure were maintained within acceptable ranges, but hypercapnia occurred during anesthesia in both groups. In conclusion, MLBP-TIVA may provide clinically useful surgical anesthesia in horses. A rapid induction with propofol may improve the qualities of induction and transition to MLBP-TIVA. | |||||
書誌情報 |
Journal of Veterinary Medical Science 巻 75, 号 2, p. 165-172, 発行日 2013-02 |
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DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1292/jvms.12-0203 | |||||
権利 | ||||||
権利情報 | ©2013 The Japanese Society of Veterinary Science | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | 日本獣医学会 | |||||
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内容記述タイプ | Other | |||||
内容記述 | Article |