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Distribution and Propagation of Hepatitis E Virus in Experimentally Infected Swine
http://hdl.handle.net/10659/1426
http://hdl.handle.net/10659/142643a830bd-4a9f-4986-b76e-29ccd3a1028a
名前 / ファイル | ライセンス | アクション |
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S-199_Hagiwara.pdf (167.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-03-11 | |||||
タイトル | ||||||
タイトル | Distribution and Propagation of Hepatitis E Virus in Experimentally Infected Swine | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
OGIWARA, Katsuro
× OGIWARA, Katsuro× Iwabu, Yukie× Kanai, Yuta× Miyasho, Taku× Daidoji, Tomo× Yunoki, Mikihiro× Tsujikawa, Muneo× Ohkubo, Yuuji× Yasue, Hiroshi× Ikuta, Kazuyoshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | HEV infections in human and pigs have been reported in many countries; however, the precise distribution and multiplication of this virus in the host remains poorly understood. In this study, we examined the distribution and multiplication of HEV genotype 3 in two piglets at the early phase of intravenous infection, and also examined the virus distribution in a naturally infected pig. We developed real-time RT-PCR to determine copy numbers of the HEV genome in the sera, feces and organs. HEV-RNA was detected in serum from a pig transiently for 7 days post-inoculation (dpi). The HEV copy numbers in the feces appearing 7 dpi were increased to 3.4x106 copies/g at 14 dpi. In contrast, the higher copy numbers of HEV were widely distributed in the tissue organs from naturally HEV-infected pig. The study showed that intravenously inoculated HEV was distributed in several restricted tissues, such as in the liver and intestine. | |||||
書誌情報 |
The Open Veterinary Science Journal 巻 1, p. 1-6, 発行日 2007-11 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1874-3188 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2174/1874318800701010001 | |||||
権利 | ||||||
権利情報 | http://creativecommons.org/licenses/by-nc/3.0/ | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Bentham Open | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |