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High Mobility Group Box 1 in Cerebrospinal Fluid From Several Neurological Diseases at Early Time Points
http://hdl.handle.net/10659/3033
http://hdl.handle.net/10659/303313345479-ea39-4c5f-9655-adcede6acfee
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-06-04 | |||||
| タイトル | ||||||
| タイトル | High Mobility Group Box 1 in Cerebrospinal Fluid From Several Neurological Diseases at Early Time Points | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Acute encephalopathy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cerebrospinal fluid | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | children | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | high mobility group box 1 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | meningitis | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Asano, Takeshi
× Asano, Takeshi× Ichiki, Kunihiko× Koizumi, Shinya× Kaizu, Kiyohiko× Hatori, Takayuki× Mashiko, Kunihiro× Sakamoto, Yuichiro× Miyasho, Taku× Fujino, Osamu× Fukunaga, Yoshitaka |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The present study aimed to elucidate the possible role of High Mobility Group Box 1 (HMGB1), which is a candidate prognostic marker in diseases that combine inflammation and tissue injury, in acute encephalopathy. HMGB1 in cerebrospinal fluid (CSF) obtained on admission from eight children with acute encephalopathy, and 16 children with febrile seizure, eight children with bacterial/aseptic meningitis, and eight children with fever without neurological symptoms were analyzed using enzyme-linked immunosorbent assay (ELISA). We found no increase in HMGB1 in CSF from acute encephalopathy or in CSF from febrile seizure or fever without neurological complications at early time points, while marked elevation of HMGB1 was seen in CSF from bacterial and aseptic meningitis. In conclusion, HMGB1 is a poor disease marker for acute encephalopathy. | |||||
| 書誌情報 |
International Journal of Neuroscience 巻 121, 号 8, p. 480-484, 発行日 2011-08 |
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| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.3109/00207454.2011.580868 | |||||
| 出版者 | ||||||
| 出版者 | Informa Healthcare | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
