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Adverse effects of maternal exposure to bisphenol F on the anxiety- and depression-like behavior of offspring
http://hdl.handle.net/10659/00005893
http://hdl.handle.net/10659/00005893f6f117ff-f5b7-4aef-b170-5121be29e6d3
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
R-2018-65_iwano.pdf (1.3 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-08-08 | |||||
| タイトル | ||||||
| タイトル | Adverse effects of maternal exposure to bisphenol F on the anxiety- and depression-like behavior of offspring | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | anxiety behavior | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | bisphenol A | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | bisphenol F | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | depression | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | endocrine disruptors | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | anxiety behavior | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | bisphenol A | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | bisphenol F | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | depression | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | endocrine disruptors | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
OHTANI, Naoko
× OHTANI, Naoko× 岩野, 英知× SUDA, Koshi× TSUJI, Erika× TANEMURA, Kentaro× INOUE, Hiroki× YOKOTA, Hiroshi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Bisphenol A (BPA), a well-known endocrine disruptor, is metabolized and eliminated rapidly from the body in adult animals. However, many authors have reported that perinatal BPA exposure alters development of the brain, reproductive system and behavior in the next generation. Recently, BPA substitutes, especially bisphenol F (BPF), have been used because of concerns about the influence of BPA on children, although the actual effects on the next generation are unknown. In this study, we observed behavioral adverse effects of the offspring of mice exposed to BPA or BPF in fetal period. Female C57BL/6 mice were given oral BPA or BPF (0 or 10 mg/kg body weight) daily from gestational day 11.5 to 18.5. The open field test, the elevated plus maze test and the forced swim test were performed at postnatal week 10. BPF exposure altered offspring behavior significantly, resulting in increases in anxiety and depressive state. The influence of BPF was stronger than that of BPA. We demonstrated novel evidence that BPF influences the behavior of offspring. | |||||
| 書誌情報 |
The Journal of veterinary medical science 巻 79, 号 2, p. 432-439, 発行日 2017-02 |
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| ISBN | ||||||
| 識別子タイプ | ISBN | |||||
| 関連識別子 | 0916-7250 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1292/jvms.16-0502 | |||||
| 権利（URI） | ||||||
| 権利情報 | https://creativecommons.org/licenses/by-nc-nd/4.0/ | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | 日本獣医学会 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
