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Complement-Related Proteins and Their Measurements: The Current Status of Clinical Investigation
http://hdl.handle.net/10659/00006987
http://hdl.handle.net/10659/0000698720aafc5c-b7e2-42fe-86b0-eec35c71e713
名前 / ファイル | ライセンス | アクション |
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R-2021-26_ohtani.pdf (670.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2022-02-21 | |||||
タイトル | ||||||
タイトル | Complement-Related Proteins and Their Measurements: The Current Status of Clinical Investigation | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
大谷, 克城
× 大谷, 克城 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Complement has been considered to be a factor that protects the host against invading microorganisms during infection. However, in recent years, complement-related protein deficiency has been found to be involved in the onset of various diseases, such as autoimmune and inflammatory diseases. In Japan, C3, C4, and CH50 tests were generally performed only when a complement system examination was necessary and there were not enough examinations for other complement factors. Since the complement system has a very complicated activation pathway, at present, it is not well known which molecule must be measured to understand the pathological condition or pathogenesis in complement-related diseases. Furthermore, since the frequency of complement factor gene alleles also differs depending on race, data from foreign countries cannot be directly applied to Japanese populations. Under these circumstances, the Japanese Association for Complement Research (JACR) has prepared approximately 20 items for complement-related examinations, including the 5 categories of functional analysis, complement factors, complement regulators, activation products, and autoantibodies. | |||||
書誌情報 |
Nephron 巻 144, 号 suppl. 1, p. 7-12, 発行日 2020-01 |
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ISBN | ||||||
識別子タイプ | ISBN | |||||
関連識別子 | 1660-8151 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1159/000512494 | |||||
権利 | ||||||
権利情報 | © 2020 S. Karger AG, Basel | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
出版者 | ||||||
出版者 | Karger AG | |||||
資源タイプ | ||||||
内容記述タイプ | Other | |||||
内容記述 | Article |