@article{oai:rakuno.repo.nii.ac.jp:00002023, author = {NOMURA, Masayuki and HOSAKA, Yoshinao and KASASHIMA, Yoshinori and UEDA, Hiromi and 植田, 弘美 and TAKEHANA, Kazushige and KUWANO, Atsutoshi and ARAI, Katsuhiko}, issue = {6}, journal = {The Journal of Veterinary Medical Science}, month = {Jun}, note = {Article, The DNA microarray analysis for matrix metalloproteinase (MMP)-related mRNA expression in equine superficial digital flexor tendinitis indicated that mRNA level of MMP-13 was apparently up-regulated in the tendinitis as compared to normal tendon. In situ hybridization also revealed that fibroblastic cells proliferated in the granulation tissue generated in the tendinitis actively expressed MMP-13 mRNA. On the other hand, in normal tendon, a few fibroblastic cells and vascular components lied in the endotenon barely expressed its mRNA, but other cellular components in the tendon bundle were not positively hybridized. As mentioned above, MMP-13 but not other collagenases or gelatinases, may play an important role in tendon injuries in the racehorses.}, pages = {637--639}, title = {Active Expression of Matrix Meralloproteinese-13 mRNA in the Granulation Tissue of Equine Superficical Digital Flexor Tendinitis}, volume = {69}, year = {2007} }