@article{oai:rakuno.repo.nii.ac.jp:00002024, author = {HAGIWARA, Seiichi and MORI, Kouichiro and OKADA, Hiroyuki and OIKAWA, Shin and 及川, 伸 and NAGAHATA, Hajime}, issue = {11}, journal = {The Journal of Veterinary Medical Science}, month = {Nov}, note = {Article, This study aimed to identify the diagnostic characteristics associated with poor prognosis and mortality in dairy cows with acute clinical Escherichia coli mastitis. On 17 dairy farms, 24 dairy cows with acute E. coli mastitis that had received therapeutic treatment were categorized into 2 groups by outcome: 17 cows that recovered (survivors) and 7 cows that died or were euthanized (non-survivors). Two days after onset of acute E. coli mastitis, dysstasia was observed in non-survivors, but not in survivors. Compared with survivors, significantly increased hematocrit (HCT) values and non-esterified fatty acid (NEFA) concentrations, and significantly decreased antithrombin activity and platelet counts were found in non-survivors on days 2 and 3 after therapy. Dysstasia, associated with decreased antithrombin activity and platelet counts, and with increased HCT and NEFA concentrations, was considered to be the major prognostic indicator associated with high mortality after therapeutic treatment in acute E. coli mastitis.}, pages = {1431--1436}, title = {Acute Escherichia coli Mastitis in Dairy Cattle: Diagnostic Parameters Associated with Poor Prognosis}, volume = {76}, year = {2014} }