{"created":"2023-06-19T07:00:53.691153+00:00","id":2380,"links":{},"metadata":{"_buckets":{"deposit":"12d58dec-a33e-4a9f-9b0e-232bf31821f5"},"_deposit":{"created_by":3,"id":"2380","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2380"},"status":"published"},"_oai":{"id":"oai:rakuno.repo.nii.ac.jp:00002380","sets":["9:27:28:29"]},"author_link":["4684","6933","4683","6931","6930","6929","6932"],"item_2_biblio_info_9":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"565","bibliographicPageStart":"561","bibliographicVolumeNumber":"74","bibliographic_titles":[{"bibliographic_title":"Journal of Veterinary Medical Science"}]}]},"item_2_description_43":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Antimicrobial administration is essential for the control and treatment of diseases in animals, but the emergence and prevalence of antimicrobial-resistant Staphylococcus aureus is a significant concern during animal production. Here we investigated the antimicrobial susceptibility of S. aureus from diseased food-producing animals and molecularly characterized the methicillin-resistant and fluoroquinolone-resistant isolates. A total of 290 S. aureus isolates obtained from cattle (n=246), swine (n=16), and chickens (n=28) between 2003 and 2009 were examined for antimicrobial susceptibility against 9 antimicrobials using an agar dilution method. Resistance to penicillin (PC) was most frequently found (24.8%), followed by oxytetracycline (OTC, 10.0%), dihydrostreptomycin (4.1%), erythromycin (EM, 3.1%), enrofloxacin (ERFX, 2.1%), and kanamycin (1.7%). The PC resistance rate was significantly higher in swine than in cattle (P<0.01) and chickens (P<0.01). The resistance rates to OTC, EM and ERFX were significantly higher in swine and chickens than in cattle (P<0.05). Methicillin-resistant S. aureus (MRSA) was recovered from milk derived from a cow with mastitis in 2003; sequence type 8, SCCmec type IV and spa type t024. In the six ERFX-resistant strains isolated after 2003, amino acid substitutions in ParC with/without GyrA were detected. As the prevalence of MRSA and FQ-resistant S. aureus in the animals should be noticed, continuous monitoring is necessary to control resistance to clinically important antimicrobials in S. aureus from food-producing animals.","subitem_description_type":"Abstract"}]},"item_2_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本獣医学会"}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1292/jvms.11-0357","subitem_relation_type_select":"DOI"}}]},"item_2_source_id_10":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0916-7250","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"BABA, Kotaro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"ISHIHARA, Kanako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OZAWA, Manao"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":""}],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"USUI, Masaru","creatorNameLang":"en"},{"creatorName":"臼井, 優","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"HIKI, Mototaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAMURA, Yutaka"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"ASAI, Tetsuo"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-09-15"}],"displaytype":"detail","filename":"S-2013-118_tamura.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"S-2013-118_tamura.pdf","url":"https://rakuno.repo.nii.ac.jp/record/2380/files/S-2013-118_tamura.pdf"},"version_id":"425c52bb-4bc5-4c7d-91ac-815befc0a458"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"antimicrobial susceptibility","subitem_subject_scheme":"Other"},{"subitem_subject":"enrofloxacin resistance","subitem_subject_scheme":"Other"},{"subitem_subject":"food-producing animals","subitem_subject_scheme":"Other"},{"subitem_subject":"methicillin resistance","subitem_subject_scheme":"Other"},{"subitem_subject":"Staphylococcus aureus","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Prevalence and Mechanism of Antimicrobial Resistance in Staphylococcus aureus Isolates from Diseased Cattle, Swine and Chickens in Japan","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Prevalence and Mechanism of Antimicrobial Resistance in Staphylococcus aureus Isolates from Diseased Cattle, Swine and Chickens in Japan"}]},"item_type_id":"2","owner":"3","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-06-16"},"publish_date":"2014-06-16","publish_status":"0","recid":"2380","relation_version_is_last":true,"title":["Prevalence and Mechanism of Antimicrobial Resistance in Staphylococcus aureus Isolates from Diseased Cattle, Swine and Chickens in Japan"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-08-31T01:58:14.462870+00:00"}