{"created":"2023-06-19T07:00:55.006932+00:00","id":2411,"links":{},"metadata":{"_buckets":{"deposit":"782d520b-7e3c-4896-8a01-a8ec952e8041"},"_deposit":{"created_by":3,"id":"2411","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2411"},"status":"published"},"_oai":{"id":"oai:rakuno.repo.nii.ac.jp:00002411","sets":["9:27:28:29"]},"author_link":["7100","7097","7095","5515","7102","7101","7094","7098","7099","7096"],"item_2_biblio_info_9":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"718","bibliographicPageStart":"713","bibliographicVolumeNumber":"74","bibliographic_titles":[{"bibliographic_title":"Journal of Veterinary Medical Science"}]}]},"item_2_description_43":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In this study, the nuclear expression of nuclear factor kappa B (NF-κB) in 48 tissues specimens from 25 canine spontaneous mammary gland tumor (MGT) patients was assessed by immunohistochemistry to compare their levels with clinical features, histological types, prognostic outcomes and proliferative activities, including the mitotic index (MI) and cylcinD1 expression. Twelve of eighteen (66.7%) malignant tumor tissues showed greater than 10% nuclear staining, while benign tumor and hyperplastic tissues showed less than 10% nuclear staining. Higher nuclear expression of NF-κB was positively correlated with larger tumor size, lymph node metastasis and higher MI; however, no correlation was observed with distant metastasis and cyclin D1 expression. Higher NF-κB nuclear expression correlated with shorter patient survival. These findings suggest that NF-κB is a useful prognostic factor for canine MGT patients.","subitem_description_type":"Abstract"}]},"item_2_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本獣医学会"}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1292/jvms.11-0380","subitem_relation_type_select":"DOI"}}]},"item_2_source_id_10":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0916-7250","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"MKAOUAR, Lobna"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"ENDO, Yoshifumi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"JUN, He Xi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"LEE, Soo-Jung"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"JAROENSONG, Tassanee"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MOCHIZUKI, Manabu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"UCHIDA, Kazuyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NAKAYAMA, Hiroyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SASAKI, Nobuo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"NAKAGAWA, Takayuki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-09-15"}],"displaytype":"detail","filename":"S-2013-119_endo.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"S-2013-119_endo.pdf","url":"https://rakuno.repo.nii.ac.jp/record/2411/files/S-2013-119_endo.pdf"},"version_id":"f54905b3-2070-4318-90fb-8361acdcfb1d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"canine MGT","subitem_subject_scheme":"Other"},{"subitem_subject":"immunohistochemistry","subitem_subject_scheme":"Other"},{"subitem_subject":"malignancy","subitem_subject_scheme":"Other"},{"subitem_subject":"NF-κB","subitem_subject_scheme":"Other"},{"subitem_subject":"prognosis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Relationship between NF-κB Expression and Malignancy of Canine Mammary Gland Tumor Tissues","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Relationship between NF-κB Expression and Malignancy of Canine Mammary Gland Tumor Tissues"}]},"item_type_id":"2","owner":"3","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-06-16"},"publish_date":"2014-06-16","publish_status":"0","recid":"2411","relation_version_is_last":true,"title":["Relationship between NF-κB Expression and Malignancy of Canine Mammary Gland Tumor Tissues"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:52:09.770267+00:00"}