{"created":"2023-06-19T07:00:57.117271+00:00","id":2461,"links":{},"metadata":{"_buckets":{"deposit":"a9e20542-4479-4284-b3fa-e94b25c25b67"},"_deposit":{"created_by":3,"id":"2461","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2461"},"status":"published"},"_oai":{"id":"oai:rakuno.repo.nii.ac.jp:00002461","sets":["9:27:28:29"]},"author_link":["7430","4748","7431"],"item_2_biblio_info_9":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"589","bibliographicPageStart":"583","bibliographicVolumeNumber":"73","bibliographic_titles":[{"bibliographic_title":"The journal of veterinary medical science"}]}]},"item_2_description_43":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Delayed wound healing is one of the complications of diabetes mellitus. The present study was performed to investigate the effect of Aloe vera oral administration on open wounds in type 2 diabetic rats. Full thickness open wounds (1.5 × 1.5 cm) were created under general anesthesia on the backs of the rats. These rats were divided into two group, a control group (Group C) and an Aloe vera oral administration group (Group A). Each wound area was measured on days 1, 2, 4 and 8 postwounding. The stages of wound granulation tissues were evaluated histopathologically. The expression of transforming growth factor (TGF)-β1 and vascular endothelial growth factor (VEGF) were determined by immunohistochemically. The wounds were significantly contracted in Group A on days 2, 4 and 8 postwounding. Histological results revealed that the inflammatory cell infiltration, angiogenesis, extracellular matrix deposition and epithelialization were promoted in Group A, respectively. The immunohistochemical results revealed that both TGF-β1 and VEGF protein-positive cells increased in Group A on day 4 postwounding. We concluded that Aloe vera oral administration accelerated wound healing in type 2 diabetic rats.","subitem_description_type":"Abstract"}]},"item_2_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本獣医学会"}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1292/jvms.10-0438","subitem_relation_type_select":"DOI"}}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ATIBA, Ayman"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"UENO, Hiroshi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"UZUKA, Yuji"}],"nameIdentifiers":[{}]}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Aloe vera","subitem_subject_scheme":"Other"},{"subitem_subject":"diabetes","subitem_subject_scheme":"Other"},{"subitem_subject":"TGF-β1","subitem_subject_scheme":"Other"},{"subitem_subject":"VEGF","subitem_subject_scheme":"Other"},{"subitem_subject":"wound healing","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The Effect of Aloe Vera Oral Administration on Cutaneous Wound Healing in Type 2 Diabetic Rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The Effect of Aloe Vera Oral Administration on Cutaneous Wound Healing in Type 2 Diabetic Rats"}]},"item_type_id":"2","owner":"3","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-06-04"},"publish_date":"2013-06-04","publish_status":"0","recid":"2461","relation_version_is_last":true,"title":["The Effect of Aloe Vera Oral Administration on Cutaneous Wound Healing in Type 2 Diabetic Rats"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:51:17.006796+00:00"}