{"created":"2023-06-19T07:01:46.002656+00:00","id":3620,"links":{},"metadata":{"_buckets":{"deposit":"abaca646-076e-4272-b89d-d44aba0d8c3f"},"_deposit":{"created_by":3,"id":"3620","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"3620"},"status":"published"},"_oai":{"id":"oai:rakuno.repo.nii.ac.jp:00003620","sets":["9:27:33:34"]},"author_link":["9212","9211","9205","9209","9210","9208","9206","9207"],"item_2_biblio_info_9":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-3","bibliographicPageEnd":"57","bibliographicPageStart":"54","bibliographicVolumeNumber":"599","bibliographic_titles":[{"bibliographic_title":"European journal of pharmacology"}]}]},"item_2_description_43":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Application of 1-oleoyl-2-acetyl-sn-glycerol (OAG), an analogue of diacylglycerol (DAG) formed via M_3 muscarinic receptors, induced inward cationic currents via a protein kinase C-independent mechanism and produced membrane depolarization with increased action potential discharges in mouse intestinal myocytes. Outside-out patches from the myocytes responded to OAG with openings of 115-pS channels characterized by a mean open time (O_τ) of 0.15 ms. M3 receptor stimulation is reportedly capable of causing brief openings (O_τ = 0.23 ms) of 120-pS cationic channels in intestinal myocytes, thus the present results strongly support the idea that the M_3-mediated 120-pS channel opening is brought about via DAG-dependent mechanisms.","subitem_description_type":"Abstract"}]},"item_2_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.ejphar.2008.09.039","subitem_relation_type_select":"DOI"}}]},"item_2_rights_16":{"attribute_name":"権利（URI）","attribute_value_mlt":[{"subitem_rights":"http://dx.doi.org/10.1016/j.ejphar.2008.09.039 | http://dx.doi.org/10.1016/j.ejphar.2008.09.039"}]},"item_2_source_id_10":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0014-2999","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sakamoto, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuyama, Hayato"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Masayuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanahashi, Yasuyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitazawa, Takio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taneike, Tetsuro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Komori, Seiichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Unno, Toshihiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-09-19"}],"displaytype":"detail","filename":"S-519_Kitazawa.pdf","filesize":[{"value":"289.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"S-519_Kitazawa.pdf","url":"https://rakuno.repo.nii.ac.jp/record/3620/files/S-519_Kitazawa.pdf"},"version_id":"5a48e2e4-3989-4aea-8c14-7fa34f06020e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"muscarinic receptor","subitem_subject_scheme":"Other"},{"subitem_subject":"M_3 subtype","subitem_subject_scheme":"Other"},{"subitem_subject":"diacylglycerol","subitem_subject_scheme":"Other"},{"subitem_subject":"cationic channels","subitem_subject_scheme":"Other"},{"subitem_subject":"intestinal smooth muscle","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A non-selective cationic channel activated by diacylglycerol in mouse intestinal myocytes","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A non-selective cationic channel activated by diacylglycerol in mouse intestinal myocytes"}]},"item_type_id":"2","owner":"3","path":["34"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-03-31"},"publish_date":"2011-03-31","publish_status":"0","recid":"3620","relation_version_is_last":true,"title":["A non-selective cationic channel activated by diacylglycerol in mouse intestinal myocytes"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T08:35:26.089792+00:00"}