{"created":"2023-06-19T07:02:56.968349+00:00","id":5158,"links":{},"metadata":{"_buckets":{"deposit":"6b9a28c1-b3ae-41a1-84b1-a89dd2b29ed6"},"_deposit":{"created_by":3,"id":"5158","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"5158"},"status":"published"},"_oai":{"id":"oai:rakuno.repo.nii.ac.jp:00005158","sets":["9:27:33:34"]},"author_link":["5064","16001","16003","16005","16007","1839","16006","16004","16002","16000","16008"],"item_2_biblio_info_9":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"976","bibliographicPageStart":"971","bibliographicVolumeNumber":"78","bibliographic_titles":[{"bibliographic_title":"The Journal of veterinary medical science"}]}]},"item_2_description_43":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The aim of the present study was to evaluate the reliability and effectiveness of directly determining endotoxin activity in plasma samples from kangaroos with lumpy jaw disease (LJD, n=15) and healthy controls (n=12). Prior to the present study, the ability of the commercially available automated handheld portable test system (PTS^<TM>) to detect endotoxin activity in kangaroo plasma was compared with that of the traditional LAL-kinetic turbidimetric (KT) assay. Plasma samples, which were obtained from endotoxin-challenged cattle, were diluted 1:20 in endotoxin-free water and heated to 80°C for 10 min. The performance of the PTS^<TM> was not significantly different from that of the traditional LAL-based assay. The data obtained using PTS^<TM> correlated with those using KT (r^2=0.963, P<0.001). These findings indicated that the PTSTM is applicable as a simplified system to assess endotoxin activity in macropods. In the present study, we demonstrated the diagnostic value of plasma endotoxin activity in kangaroos with systemic inflammation caused by oral necrobacillosis and identified plasma endotoxin activity as a sensitive marker of systemic inflammation in kangaroos with LJD. Based on ROC curves, we proposed a diagnostic cut-off point for endotoxin activity of >0.22 EU/ml for the identification of LJD. Our results indicate that the assessment of plasma endotoxin activity is a promising diagnostic tool for determining the outcome of LJD in captive macropods. ","subitem_description_type":"Abstract"}]},"item_2_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本獣医学会"}]},"item_2_relation_11":{"attribute_name":"ISBN","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"0916-7250","subitem_relation_type_select":"ISBN"}}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"http://doi.org/10.1292/jvms.15-0513","subitem_relation_type_select":"DOI"}}]},"item_2_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"SOTOHIRA, Yukari"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SUZUKI, Kazuyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SASAKI, Haruka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SANO, Tadashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TSUCHIYA, Masakazu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SUZUKI, Yohko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SHIMAMORI, Toshio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TSUKANO, Kenji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SATO, Ayano"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"YOKOTA, Hiroshi"}],"nameIdentifiers":[{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":""}],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"浅川, 満彦","creatorNameLang":"ja"},{"creatorName":"ASAKAWA, Mitsuhiko","creatorNameLang":"en"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-04-12"}],"displaytype":"detail","filename":"R-2017-74_Asakawa.pdf","filesize":[{"value":"906.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"R-2017-74_Asakawa.pdf","url":"https://rakuno.repo.nii.ac.jp/record/5158/files/R-2017-74_Asakawa.pdf"},"version_id":"60ca1eaa-9b43-46d5-b886-1716fa96f33a"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Plasma endotoxin activity in kangaroos with oral necrobacillosis (lumpy jaw disease) using an automated handheld testing system","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Plasma endotoxin activity in kangaroos with oral necrobacillosis (lumpy jaw disease) using an automated handheld testing system"}]},"item_type_id":"2","owner":"3","path":["34"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-04-12"},"publish_date":"2018-04-12","publish_status":"0","recid":"5158","relation_version_is_last":true,"title":["Plasma endotoxin activity in kangaroos with oral necrobacillosis (lumpy jaw disease) using an automated handheld testing system"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-08-31T01:23:56.401190+00:00"}