@article{oai:rakuno.repo.nii.ac.jp:00005221, author = {土谷, 佳之 and 宇山, 環 and 薮田, 拓生 and 三浦, 新平 and 加藤, 敏英}, issue = {6}, journal = {家畜診療}, month = {Jun}, note = {Article, 管内大規模酪農場において,Salmonella O4群を原因とする子牛の腸炎による死亡事故が多発したため,新生子へサルモネラ症不活化ワクチン接種を行った、,ワクチンは,出生翌日または3日齢およびその3週後に接種した。その結果,死亡率は接種開始前24週間の32.8%(40/122)から開始後24週間の6.9%(9/131)に有意に低下した (P<0.01)。また,月毎の治療率(月出生頭数の内,治療した個体の割合)は,徹底した消毒直後に低下する傾向が認められた。通常,ワクチンは,血中の移行抗体価が高い若齢期には接種すべきでないとされているが,今回,子牛のサルモネラ症に対しては出生直後のワクチン接種により臨床的な効果が得られたことから,このワクチンが子牛の免疫に何らかの影響を及ぼしたことが示1唆された。, Newborn calves at a large-scale dairy farm in the jurisdictional area were given inactivated vaccine shots because of the high fatality of calves with enteritis caused by the O4 group of Salmonella. The vaccine was given to calves on the next day of birth or at 3 days of age, and again at 3 weeks after the first shot. The fatality rate significantly dropped from 32.8% (40/122) at 24 weeks before vaccination to 6.9% (9/131) at 24 weeks after vaccination (P<0.01). The monthly treatment rate (percentage of treated calves in newborn calves, calculated monthly) was found to drop immediately after thorough disinfection. In general, vaccination is considered bad for young calves because they have high blood maternal antibody titer. However, given that clinical effectiveness of vaccination immediately after birth for salmonellosis in calves was obtained, it suggests that salmonella vaccine has some kind of effect on the immunity of calves.}, pages = {339--347}, title = {サルモネラ症による子牛の死亡事故が多発した酪農場における新生子へのワクチン接種効果}, volume = {63}, year = {2016} }