@article{oai:rakuno.repo.nii.ac.jp:00005681, author = {NAKASHIMA, Ryuji and KAWAMOTO, Masaomi and MIYAZAKI, Shigeru and ONISHI, Rumiko and FURUSAKI, Koichi and OSAKI, Maho and KIRISAWA, Rikio and SAKUDO, Akikazu and ONODERA, Takashi}, issue = {5}, journal = {The Journal of veterinary medical science}, month = {May}, note = {Article, In this study, the virucidal effect of a novel electrically charged disinfectant CAC-717 was investigated. CAC-717 is produced by applying an electric field to mineral water containing calcium hydrogen carbonate to generate mesoscopic crystals. Virus titration analysis showed a >3 log reduction of influenza A viruses after treatment with CAC-717 for 1 min in room temperature, while infectivity was undetectable after 15 min treatment. Adding bovine serum albumin to CAC-717 solution did not affect the disinfectant effect. Although CAC-717 is an alkaline solution (pH=12.39), upon contact with human tissue, its pH becomes almost physiological (pH 8.84) after accelerated electric discharge, which enables its use against influenza viruses. Therefore, CAC-717 may be used as a preventative measure against influenza A viruses and for biosecurity in the environment.}, pages = {939--942}, title = {Evaluation of calcium hydrogen carbonate mesoscopic crystals as a disinfectant for influenza A viruses}, volume = {79}, year = {2017} }