@article{oai:rakuno.repo.nii.ac.jp:00006068,
 author = {HARA, Asuka and ABE, Tomoyuki and HIRAO, Atsushi and SANBE, Kazuhiro and AYAKAWA, Hiromichi and SARANTONGLAGA, Borjigin and YAMAGUCHI, Mio and SATO, Akane and KHURCHABILIG, Atchalalt and OGATA, Kazuko and 福森, 理加 and SUGITA, Shoei and NAGAO, Yoshikazu},
 issue = {2},
 journal = {Journal of Veterinary Medical Science},
 month = {Feb},
 note = {Article, In order to obtain more information on the development of bovine and ovine fetal mammary glands, a series of mammary glands from fetuses of different ages were analyzed. A total of 16 bovine fetuses with curved crown rump lengths ranging from 12 cm (80 days) to 75 cm (240 days) and 15 ovine fetuses ranging from 55 days to 131 days were examined. We used hematoxylin and eosin stain and Oil-Red-O stain to analyze the developmental and morphogenetic processes of mammary glands. In addition, we used immunohistochemical staining to determine the pattern of expression of cytokeratin 18 (CK18) during luminal epithelial differentiation, α-smooth-muscle actin (α-SMA) for myoepithelial differentiation, Ki-67 for cell proliferation, and estrogen receptor α (ERα). Our analyzes showed: (a) The primary mammary duct begin to proliferate in a lengthwise within the teat at 90 days in bovine fetuses and 63 days in ovine fetus; (b) luminal epithelial cells and myoepithelial cells appeared from 90 days in bovine fetuses and 63 days in ovine fetus; (c) proliferation of epithelial cells appeared to coincide with the development of the primary and secondary ducts; and (d) ERα was not found in the fetal mammary gland, but adipocytes showed the presence of ERα. Overall, these results indicate that the sequence of events in the prenatal development of the mammary gland of sheep is similar to that of cattle.},
 pages = {263--271},
 title = {Histochemical properties of bovine and ovine mammary glands during fetal development},
 volume = {80},
 year = {2018},
 yomi = {FUKUMORI, Rika}
}