{"created":"2023-06-19T07:03:40.689404+00:00","id":6079,"links":{},"metadata":{"_buckets":{"deposit":"10560070-5565-4b32-ae26-7cd1cb77585c"},"_deposit":{"created_by":3,"id":"6079","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"6079"},"status":"published"},"_oai":{"id":"oai:rakuno.repo.nii.ac.jp:00006079","sets":["9:27:28:29"]},"author_link":["19448","19449","19446","19445","19447","4638"],"item_2_biblio_info_9":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-05","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"818","bibliographicPageStart":"814","bibliographicVolumeNumber":"80","bibliographic_titles":[{"bibliographic_title":"Journal of Veterinary Medical Science"}]}]},"item_2_description_43":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Ehlers-Danlos syndrome (EDS) is a group of hereditary diseases caused by mutation of extracellular matrix-related genes. Recently, spondylodysplastic EDS-Zip13 (spEDS-Zip13: OMIM 612350) was recognized as a new EDS type. This current study could reveal various morphometric differences of collagenous population in the proper substance of cornea between the wild type and spEDS-Zip13-knockout (Zip13-KO) mice. Blockade of Smad-signaling pathway might initiate these alterations. Predilected dissimilarity in level of transcriptional activity probably dictated morphology of keratocyte and shape and electron density of its nucleus. In addition, the imbalance of proteoglycans and glycosaminoglycans would also affect the diameter and arrangement of collagen fibrils. These findings would be considered as vulnerable characteristics of corneal stroma of the Zip13-KO mice.","subitem_description_type":"Abstract"}]},"item_2_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本獣医学会"}]},"item_2_relation_11":{"attribute_name":"ISBN","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"0916-7250","subitem_relation_type_select":"ISBN"}}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1292/jvms.18-0019","subitem_relation_type_select":"DOI"}}]},"item_2_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2018 The Japanese Society of Veterinary Science"}]},"item_2_rights_16":{"attribute_name":"権利（URI）","attribute_value_mlt":[{"subitem_rights":"https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja"}]},"item_2_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"HIROSE, Takuya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"SUZUKI, Ippei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKAHASHI, Naoki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"FUKADA, Toshiyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TANGKAWATTANA, Prasarn"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"TAKEHANA, Kazushige"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-26"}],"displaytype":"detail","filename":"R-2019-61_takehana.pdf","filesize":[{"value":"2.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"R-2019-61_takehana.pdf","url":"https://rakuno.repo.nii.ac.jp/record/6079/files/R-2019-61_takehana.pdf"},"version_id":"900c856d-1548-45df-8b52-86c345fa4e80"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"collagen fibril","subitem_subject_scheme":"Other"},{"subitem_subject":"cornea","subitem_subject_scheme":"Other"},{"subitem_subject":"morphometry","subitem_subject_scheme":"Other"},{"subitem_subject":"Slc39a13/Zip13-knockout mice","subitem_subject_scheme":"Other"},{"subitem_subject":"collagen fibril","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cornea","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"morphometry","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Slc39a13/Zip13-knockout mice","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Morphometric analysis of cornea in the Slc39a13/Zip13-knockout mice","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Morphometric analysis of cornea in the Slc39a13/Zip13-knockout mice"}]},"item_type_id":"2","owner":"3","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-02-26"},"publish_date":"2020-02-26","publish_status":"0","recid":"6079","relation_version_is_last":true,"title":["Morphometric analysis of cornea in the Slc39a13/Zip13-knockout mice"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-19T07:48:03.859815+00:00"}