{"created":"2023-06-19T07:03:55.218471+00:00","id":6411,"links":{},"metadata":{"_buckets":{"deposit":"4dc2c539-a883-423e-9b88-186d1b0a19d5"},"_deposit":{"created_by":3,"id":"6411","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"6411"},"status":"published"},"_oai":{"id":"oai:rakuno.repo.nii.ac.jp:00006411","sets":["9:27:28:29"]},"author_link":["4871","20519","20520","4526","6940","8032"],"item_2_biblio_info_9":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-09","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"373","bibliographicPageStart":"369","bibliographicVolumeNumber":"63","bibliographic_titles":[{"bibliographic_title":"Journal of veterinary research"}]}]},"item_2_description_43":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction: The characteristics of immune factors in somatic cells from lactating dairy cows and their association with commensal bacteria in normal milk have not been clarified. This study investigated the relationship between the pathogenic bacteria in milk and somatic cell immune factors in healthy lactating cows. Material and Methods: In total 44 healthy Holstein cows were studied on one farm. Milk samples were collected aseptically using a cannula and these samples were cultured for detection of bacteria and analysis of mRNA of immune factors expressed by somatic cells. Cows were divided into two groups based on the microbial status of their milk samples: 12 cows showed bacteria in cultures (positive group), and the other 32 cows did not (negative group). Results: The mRNA levels of IL-6, lactotransferrin, and cathelicidin expressed by somatic cells after milking decreased significantly compared to those before milking in both groups (P < 0.05). There were significantly lower mRNA levels of IL-6 and cathelicidin in the positive group compared to those in the negative group before milking. Conclusion: These results suggest that mRNA levels of IL-6 and cathelicidin expressed by the somatic cells may be affected by the presence of bacteria in healthy lactating dairy cows.","subitem_description_type":"Abstract"}]},"item_2_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"National Veterinary Research Institute in Pulawy"}]},"item_2_relation_11":{"attribute_name":"ISBN","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"2450-7393","subitem_relation_type_select":"ISBN"}}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2478/jvetres-2019-0042","subitem_relation_type_select":"DOI"}}]},"item_2_rights_16":{"attribute_name":"権利（URI）","attribute_value_mlt":[{"subitem_rights":"http://creativecommons.org/licenses/by-nc-nd/3.0 | http://creativecommons.org/licenses/by-nc-nd/3.0"}]},"item_2_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ohtsuka, Hiromichi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Hirose, Honami"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Murakami, Kenji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Murata, Ryo"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Kato, Toshihide"}],"nameIdentifiers":[{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":""}],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"田島, 誉士","creatorNameLang":""}],"familyNames":[{"familyNameLang":""}],"givenNames":[{"givenNameLang":""}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-11-18"}],"displaytype":"detail","filename":"R-2020-99_tajima.pdf","filesize":[{"value":"576.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"R-2020-99_tajima.pdf","url":"https://rakuno.repo.nii.ac.jp/record/6411/files/R-2020-99_tajima.pdf"},"version_id":"fc0ec45f-553d-4a02-b6b5-8606e8fc14c8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"cows","subitem_subject_scheme":"Other"},{"subitem_subject":"milk","subitem_subject_scheme":"Other"},{"subitem_subject":"bacteria","subitem_subject_scheme":"Other"},{"subitem_subject":"immune factor","subitem_subject_scheme":"Other"},{"subitem_subject":"somatic cells","subitem_subject_scheme":"Other"},{"subitem_subject":"cows","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"milk","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"bacteria","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"immune factor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"somatic cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Relationship between mRNA of immune factors expressed by milk somatic cells and bacteria present in healthy lactating Holstein cows","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Relationship between mRNA of immune factors expressed by milk somatic cells and bacteria present in healthy lactating Holstein cows"}]},"item_type_id":"2","owner":"3","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-11-18"},"publish_date":"2020-11-18","publish_status":"0","recid":"6411","relation_version_is_last":true,"title":["Relationship between mRNA of immune factors expressed by milk somatic cells and bacteria present in healthy lactating Holstein cows"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-08-31T01:19:41.268250+00:00"}