@article{oai:rakuno.repo.nii.ac.jp:00006466, author = {USUI, Masaru and 臼井, 優 and KAJINO, Akari and KON, Michiha and FUKUDA, Akira and SATO, Tomomi and SHIRAKAWA, Takahiro and KAWANISHI, Michiko and HARADA, Kazuki and NAKAJIMA, Chie and SUZUKI, Yasuhiko and TAMURA, Yutaka}, issue = {5}, journal = {Journal of Veterinary Medical Science}, month = {May}, note = {Article, The emergence and spread of aminoglycoside-resistant bacteria are a public health concern. The acquisition of the genes encoding 16S rRNA methylases, such as armA, rmtA, and rmtB, confers high-level resistance to aminoglycosides. However, the prevalence has not been well investigated in Japanese veterinary fields. To determine the prevalence of 16S rRNA methylases in animals, we detected 16S rRNA methylases genes in Gram-negative bacteria from animals. Here, we report the isolation of rmtB amd armA from two of the 446 Escherichia coli (0.5%) and one of the 103 Klebsiella spp. isolates (1.0%) from companion animals, respectively. However, none of the isolations were observed from 2445 E. coli isolates derived from livestock in Japan. The prevalence of 16S rRNA methylases in animals, especially in companion animals, should be carefully monitored in Japanese veterinary fields to avoid the spreading of the genes.}, pages = {874--878}, title = {Prevalence of 16S rRNA methylases in Gram-negative bacteria derived from companion animals and livestock in Japan}, volume = {81}, year = {2019} }