{"created":"2023-06-19T07:04:11.706242+00:00","id":6760,"links":{},"metadata":{"_buckets":{"deposit":"e4e61a2c-72a7-4505-8a41-578001ef8cbe"},"_deposit":{"created_by":3,"id":"6760","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"6760"},"status":"published"},"_oai":{"id":"oai:rakuno.repo.nii.ac.jp:00006760","sets":["9:27:28:29"]},"author_link":["19414","5069","21901","21902","21900"],"item_2_biblio_info_9":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"309","bibliographicPageStart":"303","bibliographicVolumeNumber":"57","bibliographic_titles":[{"bibliographic_title":"The Journal of Poultry Science"}]}]},"item_2_description_43":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_2_description_6":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The nasal mucosa plays an important role in the immune system, with nasal mucous cells secreting mucin that, along with pili, exclude foreign substances from intervening. Nasal mucosal-associated lymphoid tissue (NALT), present in the nasal lamina propria, acts as a local immune system. In birds, the Harderian gland in the orbit also plays an important role in the local immune system. In this study, we analyzed the pathway from the nasolacrimal duct to the nasal cavity in chickens and the distribution of the nasal mucous cells responsible for defense mechanisms against pathogens. To determine the three-dimensional structure of the pathway from the nasolacrimal duct to the nasal cavity, we made casts of the anatomy by injecting an acrylic resin into the area. We then prepared paraffin sections to determine the distribution of the NALT and mucous cells. The mucous gland was clearly seen in the mucosal epithelium of the nasal cavity, suggesting that the pathway along the nasal cavity develops a nonspecific immune system to deal with large foreign substances, such as bacteria, using mucins that are secreted from the mucous glands. Hence, there is not only a physical barrier but also an antibacterial activity. Unlike in other animals, morphologically, the nasolacrimal duct in chicken becomes the ventral nasal meatus and opens into the choanae in the caudal portion of the nasal cavity. NALT was prominently present in the lamina propria of the ventral nasal meatus, suggesting the presence of a specific immune system protecting against avian viruses. Thus, responses to vaccine stimulation could be developed from tissues along the pathway of the ventral nasal meatus via the nasolacrimal duct running from the punctum. These morphological studies suggest that the instillation of eye drops could be used as an efficient vaccination method for avoiding respiratory diseases.","subitem_description_type":"Abstract"}]},"item_2_publisher_36":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japan Poultry Science Association"}]},"item_2_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.2141/jpsa.0190091","subitem_relation_type_select":"DOI"}}]},"item_2_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2020 by Japan Poultry Science Association"}]},"item_2_rights_16":{"attribute_name":"権利（URI）","attribute_value_mlt":[{"subitem_rights":"https://creativecommons.org/licenses/by-nc-sa/4.0/ | https://creativecommons.org/licenses/by-nc-sa/4.0/"}]},"item_2_version_type_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":""}],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Watanabe, Takafumi","creatorNameLang":"en"},{"creatorName":"渡邉, 敬文","creatorNameLang":"ja"}],"familyNames":[{},{}],"givenNames":[{},{}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Takahashi, Naoki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Minaguchi, Jun"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Mochizuki, Ayaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hiramatsu, Kohzy"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-21"}],"displaytype":"detail","filename":"R-2021-43_watanabe.pdf","filesize":[{"value":"3.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"R-2021-43_watanabe.pdf","url":"https://rakuno.repo.nii.ac.jp/record/6760/files/R-2021-43_watanabe.pdf"},"version_id":"e1b03c21-c002-452e-9a66-6b5d17f65690"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"chicken","subitem_subject_scheme":"Other"},{"subitem_subject":"nasal cavity","subitem_subject_scheme":"Other"},{"subitem_subject":"nasolacrimal duct","subitem_subject_scheme":"Other"},{"subitem_subject":"vaccination","subitem_subject_scheme":"Other"},{"subitem_subject":"chicken","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"nasal cavity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"nasolacrimal duct","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"vaccination","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens"}]},"item_type_id":"2","owner":"3","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-21"},"publish_date":"2022-02-21","publish_status":"0","recid":"6760","relation_version_is_last":true,"title":["Three-Dimensional Analysis of the Nasolacrimal Duct and Nasal Cavity and Arrangement of Mucosal Tissue in Chickens"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-08-31T02:06:19.655375+00:00"}