@article{oai:rakuno.repo.nii.ac.jp:00007229, author = {NISHI, Koji and Gondaira, Satoshi and 権平, 智 and OKAMOTO, Mariko and MATSUDA, Kazuya and 松田, 一哉 and SATO, Ayano and 佐藤, 綾乃 and KATO, Toshihide and SASAGAWA, Misawo and TANAKA, Takahiro and 樋口, 豪紀}, issue = {1}, journal = {Journal of Veterinary Medical Science}, month = {}, note = {Article, Bovine Mycoplasma arthritis (MA) is caused by Mycoplasma bovis and exhibits severe clinical symptoms. However, the pathophysiology of bovine MA is incompletely understood. In this study, we examined the cytokine mRNA expression of synovial fluid (SF) cells and cytokine concentrations in the SF of MA calves. The SF was isolated from five clinically healthy (control) and seven MA calves. mRNA and protein levels of interleukin (IL)-1β, IL-6, IL-8, IL-12, and IL-17 in the SF from MA calves were significantly higher than those from control calves. Our results indicate that SF cells produce inflammatory cytokines, which mainly contribute to the severe inflammatory response in the joints of the MA calves.}, pages = {31--35}, title = {Inflammatory cytokine mRNA and protein levels in the synovial fluid of Mycoplasma arthritis calves}, volume = {83}, year = {2021} }