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Active Expression of Matrix Meralloproteinese-13 mRNA in the Granulation Tissue of Equine Superficical Digital Flexor Tendinitis
http://hdl.handle.net/10659/1428
http://hdl.handle.net/10659/1428e3a3915b-fcc4-463d-ab62-4043fb3047c1
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-03-11 | |||||
タイトル | ||||||
タイトル | Active Expression of Matrix Meralloproteinese-13 mRNA in the Granulation Tissue of Equine Superficical Digital Flexor Tendinitis | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
NOMURA, Masayuki
× NOMURA, Masayuki× HOSAKA, Yoshinao× KASASHIMA, Yoshinori× 植田, 弘美× TAKEHANA, Kazushige× KUWANO, Atsutoshi× ARAI, Katsuhiko |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The DNA microarray analysis for matrix metalloproteinase (MMP)-related mRNA expression in equine superficial digital flexor tendinitis indicated that mRNA level of MMP-13 was apparently up-regulated in the tendinitis as compared to normal tendon. In situ hybridization also revealed that fibroblastic cells proliferated in the granulation tissue generated in the tendinitis actively expressed MMP-13 mRNA. On the other hand, in normal tendon, a few fibroblastic cells and vascular components lied in the endotenon barely expressed its mRNA, but other cellular components in the tendon bundle were not positively hybridized. As mentioned above, MMP-13 but not other collagenases or gelatinases, may play an important role in tendon injuries in the racehorses. | |||||
書誌情報 |
The Journal of Veterinary Medical Science 巻 69, 号 6, p. 637-639, 発行日 2007-06 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0916-7250 | |||||
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出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
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出版者 | 日本獣医学会 | |||||
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内容記述タイプ | Other | |||||
内容記述 | Article |