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Effectiveness of Isoprothiolane in Preventing Fatty Liver in Dairy Cows
http://hdl.handle.net/10659/3840
http://hdl.handle.net/10659/3840359c7e34-86a9-4bc0-b57f-067d70907b41
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
S-2014-183_minaguchi.pdf (2.7 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2015-05-12 | |||||
| タイトル | ||||||
| タイトル | Effectiveness of Isoprothiolane in Preventing Fatty Liver in Dairy Cows | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Fatty liver | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | isoprothiolane | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | beta-oxidation | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Minaguchi, Jun A.
× Minaguchi, Jun A.× Miura, Michisaburo× Oikawa, Shin× Handa, Fumi× Haraguchi, Takuya× Miyamoto-Ohno, Kazuyoshi× Ito, Yuta× Hosaka, Yoshinao Z.× Ueda, Hiromi× Takehana, Kazushige |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In this study, we evaluated the effectiveness of isoprothiolane in preventing fatty liver in dairy cows. Eight pregnant Holstein cows with high body condition scores were studied. Four cows were administered isoprothiolane via feed at 10 g/day/head from 21 days before delivery (treated group), while the remaining four cows received no treatment (non-treated group). Liver samples from both groups were obtained 21 days before delivery and 2 days following delivery. No accumulation of lipid droplets in hepatocytes was observed in any cows prior to delivery. Following delivery, the accumulation of lipid droplets in hepatocytes was significantly reduced in the treated group compared to the non-treated group. The number of mitochondria per unit area was also significantly smaller in the treated group than in the non-treated group. Blood and biochemical test results from cows in the treated group showed an increase in mGOT levels and stable intrahepatic ATP production. These results suggest that isoprothiolane treatment intensified beta-oxidation in liver mitochondria, thereby activating the TCA cycle and maintaining intrahepatic ATP production. | |||||
| 書誌情報 |
The Open Veterinary Science Journal 巻 7, p. 1-5, 発行日 2013-02 |
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| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.2174/1874318801307010001 | |||||
| 権利 | ||||||
| 権利情報 | © Minaguchi et al.; Licensee Bentham Open. This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | BENTHAM OPEN | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
