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  1. 1:大学
  2. 2.獣医学群
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  4. 学術論文(雑誌)

Functional Disorder of the Retina in Manganese-Deficient Japanese Quail Revealed by Electroretinography using a Contact Lens Electrode with Built-In Light Source

http://hdl.handle.net/10659/1840
http://hdl.handle.net/10659/1840
a731f5a9-21c3-4077-a483-8006050c7f4f
名前 / ファイル ライセンス アクション
S-541_Teraoka.pdf S-541_Teraoka.pdf (1.1 MB)
Item type 学術雑誌論文 / Journal Article(1)
公開日 2011-03-31
タイトル
タイトル Functional Disorder of the Retina in Manganese-Deficient Japanese Quail Revealed by Electroretinography using a Contact Lens Electrode with Built-In Light Source
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 ENDO, Kentaro

× ENDO, Kentaro

WEKO 5851

ENDO, Kentaro

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ITOH, Norihiko

× ITOH, Norihiko

WEKO 5852

ITOH, Norihiko

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MAEHARA, Seiya

× MAEHARA, Seiya

WEKO 5213
教員総覧 d7ba092ba8f1bb51

MAEHARA, Seiya

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SHINOZAKI, Aya

× SHINOZAKI, Aya

WEKO 5853

SHINOZAKI, Aya

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IMAGAWA, Tomohiro

× IMAGAWA, Tomohiro

WEKO 5854

IMAGAWA, Tomohiro

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UEHARA, Masato

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WEKO 5855

UEHARA, Masato

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MIZUNO, Naoharu

× MIZUNO, Naoharu

WEKO 5856

MIZUNO, Naoharu

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SASAKI, Shoji

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WEKO 5857

SASAKI, Shoji

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HIRAGA, Takeo

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WEKO 5858

HIRAGA, Takeo

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TERAOKA, Hiroki

× TERAOKA, Hiroki

WEKO 5859
教員総覧 9426



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内容記述タイプ Abstract
内容記述 Manganese deficiency results in neurological and skeletal defects, together with ultrastructural disarrangement of the retina in rats. Wild birds show a range of Mn concentrations in their tissues, including the liver, raising the possibility of Mn-related disorders in the wild. Electroretinography (ERG) provides a useful noninvasive approach to evaluate visual function. This method is especially useful in birds, as objective analysis of them is very difficult, while they have well-developed vision. In this study, we carried out a convenient and reliable ERG recording using a contact lens electrode with a built-in light source (LED electrode) of Japanese quail (Coturnix coturnix japonica) fed a Mn-deficient diet. After 10 min light adaptation, single-flash and flicker cone responses were reproducibly recorded to cause an intensity-dependent increase in amplitude of both a-wave and b-wave in single-flash ERG. Mn-deficient feeding markedly decreased the Mn concentration in the liver by almost half in 3 to 6 weeks, followed by body weight loss in 13 to 15 weeks. Implicit time of a-wave and b-wave cone response by single-flash stimulation was significantly delayed in quail with a Mn depletion from 3 to 6 weeks. Every cone response of the Mn-deprived quail had a tendency to decrease amplitude. The ultrastructure of cone photoreceptor cells was disorganized by Mn deficiency, including changes in outer segment discs of photoreceptor cells. These results suggest the essential role of Mn in the integrity of the retinal function of birds.
書誌情報 The journal of veterinary medical science

巻 70, 号 2, p. 139-144, 発行日 2008-02
ISSN
収録物識別子タイプ ISSN
収録物識別子 0916-7250
DOI
関連タイプ isIdenticalTo
識別子タイプ DOI
関連識別子 10.1292/jvms.70.139
著者版フラグ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
出版者
出版者 日本獣医学会
資源タイプ
内容記述タイプ Other
内容記述 Article
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