| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2024-03-26 |
| タイトル |
|
|
タイトル |
Relationship between Escherichia coli virulence factors, notably kpsMTII, and symptoms of clinical metritis and endometritis in dairy cows |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Escherichia coli |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
kpsMTII |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
postpartum uterine disease |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
uterine restoration time |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
virulence factor |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
YAMAMURA, Fuminosuke
SUGIURA, Tomochika
MUNBY, Montgomery
SHIOKURA, Yusei
MURATA, Ryo
NAKAMURA, Tomohiro
FUJIKI, Jumpei
IWANO, Hidetomo
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Although Escherichia coli is a commensal bacterium of the bovine vaginal microbiota, it is an important pathogenic bacterium that causes diseases of the reproductive tract and sub-fertility. Recent studies have focused on virulence factors (VFs) of intrauterine E. coli; however, actual endometrial VFs have not been clearly identified. The purpose of this study was to identify the VFs of E. coli associated with clinical metritis and endometritis. Thirty-two strains of E. coli and four mixed Trueperella pyogenes (TP) strains were detected in the uterus of 19 Holstein dairy cows with obvious clinical signs (between 8 and 66 days postpartum). The presence of six E. coli VFs (fimH, fyuA, kpsMTII, hra1, csgA, and astA) was examined by PCR, and clinical signs and reproductive performance (mixed TP, the percentage of polymorphonuclear neutrophils [PMN%], days to uterine involution, etc.) were evaluated. Four VFs (fimH, hra1, csgA, and astA) were detected in all E. coli strains, whereas fyuA and kpsMTII were detected in 94% and 50% of strains, respectively. Cows with E. coli strains harboring kpsMTII exhibited significantly severe clinical scores (vaginal discharge score, PMN%, uterine involution), suggesting that kpsMTII is a key VF for progression of clinical metritis and endometritis. In the present study, we clearly identified six VFs associated with clinical metritis and endometritis. In addition, E. coli strains with kpsMTII probably play a crucial role in the progression of clinical metritis and endometritis. |
|
言語 |
en |
| 書誌情報 |
en : Journal of Veterinary Medical Science
巻 84,
号 3,
p. 420-428,
発行日 2022
|
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1292/jvms.21-0586 |
| 権利 |
|
|
言語 |
en |
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
権利情報 |
Creative Commons Attribution 4.0 International |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
日本獣医学会 |
|
言語 |
ja |
| 資源タイプ |
|
|
内容記述タイプ |
Other |
|
内容記述 |
journal article |
|
言語 |
en |
R-2023-151_iwano.pdf
