| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-03-10 |
| タイトル |
|
|
タイトル |
Nationwide analysis of antimicrobial resistance in pathogenic Escherichia coli strains isolated from diseased swine over 29 years in Japan |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
apramycin |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
bicozamycin |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
multidrug-resistant |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
pathogenic Escherichia coli |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
swine |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
Kusumoto, Masahiro
Tamamura-Andoh, Yukino
Hikoda-Kogiku, Yuna
Magome, Asami
Okuhama, Erina
Sato, Keisuke
Mizuno, Yoshino
Arai, Nobuo
Watanabe-Yanai, Ayako
Iwata, Taketoshi
Ogura, Yoshitoshi
Gotoh, Yasuhiro
Nakamura, Keiji
Hayashi, Tetsuya
Akiba, Masato
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Pathogenic Escherichia coli strains are important causes of several swine diseases that result in significant economic losses worldwide. In Japan, the use of antimicrobials in swine is much higher than that in other farm animals every year. Antimicrobial resistance in pathogenic E. coli strains also heavily impacts the swine industry due to the limited treatment options and an increase in the potential risk of the One Health crisis. In 2016, we investigated 684 Japanese isolates of swine pathogenic E. coli belonging to four major serogroups and reported the emergence and increase in the highly multidrug-resistant serogroups O116 and OSB9 and the appearance of colistin-resistant strains. In the present study, by expanding our previous analysis, we determined the serotypes and antimicrobial resistance of 1,708 E. coli strains isolated from diseased swine between 1991 and 2019 in Japan and found recent increases in the prevalences of multidrug-resistant strains and minor serogroup strains. Among the antimicrobials examined in this study that have been approved for animal use, a third-generation cephalosporin was found to be effective against the most isolates (resistance rate: 1.2%) but not against highly multidrug-resistant strains. We also analyzed the susceptibilities of the 1,708 isolates to apramycin and bicozamycin, both which are available for treating swine in Japan, and found that the rates of resistance to apramycin and bicozamycin were low (6.7% and 5.8%, respectively), and both antimicrobials are more effective (resistance rates: 2.7% and 5.4%, respectively) than third-generation cephalosporins (resistance rate: 16.2%) against highly multidrug-resistant strains. |
|
言語 |
en |
| 書誌情報 |
en : Frontiers in Microbiology
巻 14,
p. 1107566-01-1107566-11,
発行日 2023-03
|
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
1664-302X |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3389/fmicb.2023.1107566 |
| 権利 |
|
|
言語 |
en |
|
権利情報Resource |
https://creativecommons.org/licenses/by/4.0/ |
|
権利情報 |
Creative Commons Attribution 4.0 International |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 |
|
|
出版者 |
Frontiers Media S.A. |
|
言語 |
en |
| 資源タイプ |
|
|
内容記述タイプ |
Other |
|
内容記述 |
journal article |
|
言語 |
en |
R-2024-251_akiba.pdf (1.8 MB)
