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Expression of monocarboxylate transporter 1(MCT1) in the dog intestine
http://hdl.handle.net/10659/1446
http://hdl.handle.net/10659/14462f62768c-37ce-4e95-b2d0-628f1dcea7e0
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
S-177_Matsuda.pdf (984.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2010-03-11 | |||||
| タイトル | ||||||
| タイトル | Expression of monocarboxylate transporter 1(MCT1) in the dog intestine | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
SHIMOYAMA, Yumiko
× SHIMOYAMA, Yumiko× KIRAT, Doaa× AKIHARA, Yuko× KAWASAKO, Kazufumi× KOMINE, Misa× HIRAYAMA, Kazuko× 松田, 一哉× 岡本, 実× 岩野, 英知× KATO, Seiyu× TANIYAMA, Hiroyuki |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In this study, the expression and distribution of monocarboxyolate transporter 1 (MCT1) along the intestines (duodenum, jejunum, ileum, cecum, colon and rectum) of dogs were investigated at both the mRNA and protein levels. The expression of MCT1 protein and its distribution were confirmed by Western blotting and immunohistochemical staining using the antibody for MCT1. We identified mRNA coding for MCT1 and a 43-kDa band of MCT1 protein in all regions from the duodenum to the rectum. Immunoreactive staining for MCT1 was also observed in epithelial cells throughout the intestines. MCT1 immunoreactivity was greater in the large intestine than in the small intestine. MCT1 protein was predominantly expressed on the basolateral membranes along intestinal epithelial cells, suggesting that MCT1 may play an important role in lactate efflux and transport of short-chain fatty acids (SCFAs) to the bloodstream across the basolateral membranes of the dog intestine. | |||||
| 書誌情報 |
The Journal of Veterinary Medical Science 巻 69, 号 6, p. 599-604, 発行日 2007-06 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0916-7250 | |||||
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| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | 日本獣医学会 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
