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Genetic Diversity in the Prion Protein Gene (PRNP) of Domestic Cattle and Water Buffaloes in Vietnam, Indonesia and Thailand
http://hdl.handle.net/10659/4288
http://hdl.handle.net/10659/428849b7d516-6c52-40cc-97e1-e847364f5e8e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
S-2015-249_muramatsu.pdf (678.7 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-05-23 | |||||
| タイトル | ||||||
| タイトル | Genetic Diversity in the Prion Protein Gene (PRNP) of Domestic Cattle and Water Buffaloes in Vietnam, Indonesia and Thailand | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | BSE | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | indel polymorphisms | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | local cattle | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | PRNP | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | SNPs | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Southeast Asia | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
UCHIDA, Leo
× UCHIDA, Leo× HERIYANTO, Agus× THONGCHAI, Chalermchaikit× HANH, Tran Thi× HORIUCHI, Motohiro× ISHIHARA, Kanako× TAMURA, Yutaka× 村松, 康和 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | There has been an accumulation of information on frequencies of insertion/deletion (indel) polymorphisms within the bovine prion protein gene (PRNP) and on the number of octapeptide repeats and single nucleotide polymorphisms (SNPs) in the coding region of bovine PRNP related to bovine spongiform encephalopathy (BSE) susceptibility. We investigated the frequencies of 23-bp indel polymorphism in the promoter region (23indel) and 12-bp indel polymorphism in intron 1 region (12indel), octapeptide repeat polymorphisms and SNPs in the bovine PRNP of cattle and water buffaloes in Vietnam, Indonesia and Thailand. The frequency of the deletion allele in the 23indel site was significantly low in cattle of Indonesia and Thailand and water buffaloes. The deletion allele frequency in the 12indel site was significantly low in all of the cattle and buffaloes categorized in each subgroup. In both indel sites, the deletion allele has been reported to be associated with susceptibility to classical BSE. In some Indonesian local cattle breeds, the frequency of the allele with 5 octapeptide repeats was significantly high despite the fact that the allele with 6 octapeptide repeats has been reported to be most frequent in many breeds of cattle. Four SNPs observed in Indonesian local cattle have not been reported for domestic cattle. This study provided information on PRNP of livestock in these Southeast Asian countries. | |||||
| 書誌情報 |
The Journal of Veterinary Medical Science 巻 76, 号 7, p. 1001-1008, 発行日 2014-07 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0916-7250 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1292/jvms.13-0642 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | 日本獣医学会 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
