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Unique morphological characteristics in the ovary of cotton rat (Sigmodon hispidus)
http://hdl.handle.net/10659/00007005
http://hdl.handle.net/10659/000070056dac4114-0794-4217-ab8d-e82a077f613e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
R-2021-63_hosotani.pdf (8.3 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
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| 公開日 | 2022-02-21 | |||||
| タイトル | ||||||
| タイトル | Unique morphological characteristics in the ovary of cotton rat (Sigmodon hispidus) | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Cotton rat | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Double nucleated oocytes | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Folliculogenesis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Multi-oocyte follicles | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Oocytogenesis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Cotton rat | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Double nucleated oocytes | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Folliculogenesis | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Multi-oocyte follicles | |||||
| キーワード | ||||||
| 言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | Oocytogenesis | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
ISLAM, Md. Rashedul
× ISLAM, Md. Rashedul× ICHII, Osamu× NAKAMURA, Teppei× IRIE, Takao× MASUM, Md. Abdul× 細谷実, 里奈× OTANI, Yuki× ELEWA, Yaser Hosny Ali× KON, Yasuhiro |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Cotton rats (Sigmodon hispidus, CRs) are commonly used as animal models in biomedical research. However, the reproductive characteristics and ovarian development in the CRs has not been widely investigated. We have previously shown that female CRs, in particular, show several unique phenotypes associated with the urogenital system, such as chronic kidney disease and pyometra. Our investigation revealed unique morphologies in CR ovaries, particularly in oocytes. Cotton rat ovaries at 6–8 weeks of age were obtained from the Hokkaido Institute of Public Health, and their sections analyzed by light microscopy and transmission electron microscopy. Although the general histology and folliculogenesis of CR ovaries were similar to those of other experimental rodents, multi-oocyte follicles (MOFs) and double nucleated oocytes (DNOs) were also observed. Although MOFs were found at all stages of follicular development, a greater frequency of MOFs was observed in the primary and secondary stages. However, DNOs tended to be frequently observed in primordial follicles. Almost all MOF oocytes and a few DNOs possessed a clear zona pellucida, expressed DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 and Forkhead box protein 2, a representative marker of oocytes and follicular epithelial cells. Thus, our investigations revealed the unique phenotypes of the CR ovary. As MOFs and DNOs are occasionally observed in human patients with infertility, the CR would be a useful animal model to study for gaining a better understanding of folliculogenesis and oocytogenesis, as well as their abnormalities in humans and other animals. | |||||
| 書誌情報 |
Journal of Reproduction and Development 巻 66, 号 6, p. 529-538, 発行日 2020 |
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| ISBN | ||||||
| 識別子タイプ | ISBN | |||||
| 関連識別子 | 0916-8818 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | https://doi.org/10.1262/jrd.2020-061 | |||||
| 権利（URI） | ||||||
| 権利情報 | https://creativecommons.org/licenses/by-nc-nd/4.0/ | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | 日本繁殖生物学会 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Article | |||||
