Item type |
学術雑誌論文 / Journal Article(1) |
公開日 |
2024-03-26 |
タイトル |
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言語 |
en |
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タイトル |
Investigating genetic redundancy as a source of genetic diversity and adaptability in the U.S. Holstein breed |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
著者 |
Steyn, Y.
Lawlor, T.J.
Tsuruta, S.
Masuda, Y.
Legarra, A.
Lourenco, D.A.L.
Misztal, I.
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抄録 |
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内容記述タイプ |
Abstract |
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内容記述 |
The continuous increase in inbreeding in the U.S. Holstein is a threat to genetic diversity. Loss of genetic diversity can hinder adaptation to changing environments and consumer demands. K-means clustering on the genomic relationship matrix was used to stratify 20,099 selected candidates into five clusters. These clusters were shown to be different through expected inbreeding within- and across cluster, the fixation index (Fst), and genetic correlations for stature between clusters. Expected inbreeding within cluster was mostly higher than across-cluster. The average Fst across cluster was 0.03. Genetic correlations ranged from <0.50 to >0.90. Families were formed by tracing pedigrees of each cluster back for 10 generations. Allele frequency changes over generations were evaluated. Polygenic shifts, selective sweeps, hitch-hiking, and epistasis were observed. The Replicate Frequency Spectrum was used to measure genetic redundancy. Results show that sub-populations within the breed have developed differently over time. |
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言語 |
en |
書誌情報 |
en : Proceedings of the 12th World Congress of Genetics Applied to Livestock Production
p. 1000-1003,
発行日 2022
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DOI |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.3920/978-90-8686-940-4_236 |
権利 |
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言語 |
en |
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権利情報Resource |
https://creativecommons.org/licenses/by/4.0/ |
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権利情報 |
Creative Commons Attribution 4.0 International |
著者版フラグ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
出版者 |
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言語 |
en |
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出版者 |
Wageningen Academic Publishers |
資源タイプ |
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内容記述タイプ |
Other |
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内容記述 |
journal article |
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言語 |
en |